10 Medications That Cause Falls in Seniors: Use with Caution

Be aware of common medications that cause falls

older adults falls each year, often causing serious injury.

To reduce your older adult’s fall risk, regular medication reviews are essential. That’s because many commonly used drugs are associated with an increase in fall risk.

Geriatrician Dr. Leslie Kernisan explains which medications to watch out for and why they could cause seniors to fall.

Having this information helps you work with your older adult’s doctor to try to reduce or eliminate the use of these drugs. At the very least, you’ll be able to confirm that the benefits of the medication is worth the risk.

In her article, Dr. Kernisan groups 10 common medications that cause falls into 3 broader categories of drugs. 

We’ve summarized the key points that explain what these drugs are used to treat, how they affect fall risk, and what to do if your older adult is taking any of these medications.

Medications that affect brain function

These drugs are often called psychoactives. They affect brain function and tend to cause drowsiness.

They can also cause or worsen confusion, especially in people with memory problems or dementia.


  • Usually prescribed to help people sleep or to help with anxiety
  • Common drugs include Ativan, Valium, Restoril, and Xanax (generic names: lorazepam, diazepam, temazepam, alprazolam)
  • Warning: It can be dangerous to stop benzodiazepines suddenly. They should always be tapered under medical supervision

2. Non-benzodiazepine prescription sedatives

  • Usually prescribed to treat insomnia or trouble with sleep
  • Common drugs include Ambien, Sonata, and Lunesta (generic names: zolpidem, zaleplon, and eszopiclone)

3. Antipsychotics

  • Sometimes prescribed to people with depression
  • Common antipsychotics are mainly second-generation, including Risperdal, Seroquel, Zyprexa, and Abilify (generic names: risperidone, quetiapine, olanzapine, and aripiprazole)
  • Haldol (haloperidol), a first-generation antipsychotic, is sometimes still used

4. Anticonvulsants (seizure medications) and mood stabilizers

  • Depakote (valproic acid) is a mood stabilizer that is sometimes used to manage difficult behaviors in Alzheimer’s or other dementias
  • Neurontin (gabapentin) is another seizure medication often used to treat nerve pain

5. Antidepressants

  • Usually prescribed to treat depression or anxiety
  • Common drugs include Zoloft, Celexa, Lexapro, Paxil, Prozac, Remeron, Wellbutrin, and Effexor (generic names: sertraline, citalopram, escitalopram, paroxetine, fluoxetine, mirtazapine, bupropion, and venlafaxine)
  • Trazodone, an older antidepressant, is typically used as a mild sleep aid

6. Opioid (narcotic) pain relievers

  • Common drugs include codeine, hydrocodone, oxycodone, morphine, fentanyl, and methadone
  • Opioids often cause drowsiness and other side-effects
  • Research linking opioids with falls have mixed results, but experts like the CDC recommend that narcotics should be evaluated when working to reduce fall risk

7. Anticholinergics

  • These drugs include: antihistamines like Benadryl, “PM” versions of over-the-counter pain relievers (Nyquil, Tylenol PM); overactive bladder medications like Ditropan and Detrol; medications for vertigo, motion sickness, or nausea like Dramamine, Antivert, Scopace, and Phenergan; anti-itch meds like Vistaril (hydroxyzine); muscle relaxants like Flexaril (cyclobenzaprine); tricyclic antidepressants and Paxil

Medications that affect blood pressure

These types of drugs can cause or worsen a sudden fall in blood pressure. A drop in blood pressure can increase fall risk by making someone feel dizzy or faint.

8. Antihypertensives

9. Other medications that affect blood pressure

  • Alpha-blockers are often prescribed to help men with enlarged prostate urinate
  • Common drugs include Flomax, Hytrin, Cardura, and Minipress (tamsulosin, terazosin, doxazosin, and prazosin)

Medications that lower blood sugar

Older adults who have diabetes take medication to lower blood sugar. Low blood sugar caused by these medications is associated with increased falls.

10. Medications that lower blood sugar

  • Most diabetes medications can cause or worsen hypoglycemia (too low blood sugar)

What to do if your senior is taking these medications

If your older adult is currently taking one of these medications, don’t make any changes without talking with their doctor. Suddenly discontinuing a drug could cause serious harm.

And even if a drug they’re taking is associated with increased fall risk, it doesn’t always mean that your older adult shouldn’t take them.

The CDC recommends that seniors STOP medications when possible, SWITCH to safer alternatives, or REDUCE medications to the lowest effective dose.

Your older adult’s doctor should carefully consider the pros and cons of using a medication linked to increased fall risk. Sometimes, the benefits to their health and well-being will be worth it.

In other cases, an alternative may be a better choice. When one of these medications is being used, doctors should regularly review the need for and dosage of those drugs.

Next Step  Get details on medications that cause falls in Dr. Kernisan’s full article at Better Health While Aging

By DailyCaring Editorial Team
Image: Helpline

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